First FDA-Approved Drug for Postpartum Depression Is Expected to Cost More Than $30,000

Written by Julia Ries on March 20, 2019

“The GABA receptors in effect turn on again — they rebound — but to a great extent, they become ‘hyperactive’ so to speak, leading to depressive symptoms,” explained Dr. Kecia Gaither, a double board-certified OB/GYN and maternal fetal medicine physician with NYC Health+Hospitals/Lincoln.

Brexanolone, which is a synthetic compound made from progesterone, acts to correct the hyperactive GABA receptors and, ultimately, reduce depressive symptoms, said Gaither.

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